SELLA AND HYPOPHYSIS

Preparatory steps:
- Indications: suspicion of sellar or hypophyseal alterations (endocrinological diseases, visual defects, alterations of ocular motility) when MRI is contra-indicated or not available. MRI is the examination of choice
- Advisable preliminary investigations: evaluation of visual function
- Patient preparation: information about the procedure: restraint from food, but not fluid, is recommended, if intravenous contrast media are to be given
- Scan projection radiograph: lateral from C2 to above skull base
1. DIAGNOSTIC REQUIREMENTS
Image criteria:
1.1 Visualization of
1.1.1 Entire hypophyseal region including osseous walls
1.1.2 Vessels after intravenous contrast media
1.2 Critical reproduction
1.2.1 Visually sharp reproduction the osseous limit of the sella
1.2.2 Visually sharp reproduction of the hypophysis and its stalk
1.2.3 Reproduction of intrahypophyseal density differences
1.2.4 Visually sharp reproduction of the chiasm and suprasellar cisterns
1.2.5 Visually sharp reproduction of the cavernous sinuses and lateral sellar regions
1.2.6 Visually sharp reproduction of the main vessels after intravenous contrast media
2. CRITERIA FOR RADIATION DOSE TO THE PATIENT
2.1 CTDIW : no specific value as yet available (for information:routine head: 60 mGy)
2.1 DLP : no specific value as yet available (for information: routine head: 1050 mGy cm)
3. EXAMPLES OF GOOD IMAGING TECHNIQUE
3.1 Patient position : supine for axial scans; supine or prone for coronal scans
3.2 Volume of investigation : from 0.5 cm below to 0.5 cm above the hypophyseal region
3.3 Nominal slice thickness : 2-3 mm
3.4 Inter-slice distance/pitch : contiguous or a pitch = 1.0
3.5 FOV : head dimension (about 24 cm); secondary reduction of FOV is necessary for evaluation of subtle pathology
3.6 Gantry tilt : OM line for axial scanning; according to the patient position for coronal scanning
3.7 X-ray tube voltage (kV) : standard
3.8 Tube current and exposure time product (mAs) : should be as low as consistent with required image quality
3.9 Reconstruction algorithm : soft tissue or high resolution
3.10 Window width : 140-300 HU (soft tissue)
2000-3000 HU (bones)
3.11 Window level : 30-40 HU (soft tissue)
200-400 HU (bones)
4. CLINICAL CONDITIONS WITH IMPACT ON GOOD IMAGING PERFORMANCE
4.1 Motion - movement artefact deteriorates image quality (prevented by head fixation or sedation of non-cooperative patients)
4.2 Intravenous contrast media - useful to identify vascular structures, enhancing lesions and alterations of blood-brain barrier
4.3 Problems and pitfalls - calcifications versus contrast enhancement
  - foreign bodies (beam hardening artefacts)
  - artefacts from dental prothesis/fillings
4.4 Modification to technique - change of gantry angulation or patient position to avoid artefact