PANCREAS

Preparatory steps:
- Indications: suspected or known focal or diffuse disease of the pancreas or peripancreatic structures
- Advisable preliminary investigations: ultrasonography; laboratory investigations (amylase, lipase). MRI may be an alternative examination without exposure to inonising radiation
- Patient preparation: information about the procedure; exclude high density contrast media from previous investigations; oral contrast media directly prior to the examination (in right lateral position) to demarcate the duodenum; restraint from food, but not fluid, is recommended, if intravenous contrast media are to be given
- Scan projection radiograph: frontal from lower chest to middle abdomen
1. DIAGNOSTIC REQUIREMENTS
Image criteria:
1.1 Visualization of
1.1.1 Entire pancreas (head, body, tail, uncinate process)
1.1.2 Entire diseased peripancreatic tissue
1.1.3 Adjacent parts of liver, spleen, bowels and stomach
1.1.4 Vessels after intravenous contrast media
1.2 Critical reproduction
1.2.1 Visually sharp reproduction of the pancreatic contours
1.2.2 Visually sharp reproduction of the pancreatic parenchyma
1.2.3 Reproduction of the pancreatic duct
1.2.4 Visually sharp reproduction of the common bile duct within the pancreatic head
1.2.5 Visually sharp reproduction of the mesenteric artery and vein
1.2.6 Visually sharp reproduction of the splenic artery and vein
1.2.7 Visually sharp reproduction of the portal vein
1.2.8 Visually sharp reproduction of the coeliac trunk
1.2.9 Visually sharp reproduction of diaphragmatic crura
1.2.10 Visually sharp reproduction of the aorta
1.2.11 Visually sharp reproduction of the vena cava
1.2.12 Visually sharp reproduction of the renal vessels
1.2.13 Visually sharp reproduction of the duodenum
2. CRITERIA FOR RADIATION DOSE TO THE PATIENT
2.1 CTDIW : no specific value as yet available (for information: routine abdomen: 35 mGy)
2.1 DLP : no specific value as yet available (for information: routine abdomen: 800 mGy cm)
3. EXAMPLES OF GOOD IMAGING TECHNIQUE
3.1 Patient position : supine with arms at chest or head level
3.2 Volume of investigation : 1-2 cm above the pancreatic tail to 1-2 cm below the uncinate process; larger volume may be needed to include all peripancreatic lesions such as pseudocysts or exudates
3.3 Nominal slice thickness : 3-5 mm; 7-10 mm in known larger lesions, serial or preferably helical
3.4 Inter-slice distance/pitch : contiguous or a pitch = 1.0; 5-10 mm or a pitch up to 1.2-2.0 for exudates caudal to the pancreas
3.5 FOV : adjusted to the largest diameter of the abdomen within the volume under investigation; secondary magnification by reducing the FOV may be necessary for evaluation of subtle pathology
3.6 Gantry tilt : none
3.7 X-ray tube voltage (kV) : standard
3.8 Tube current and exposure time product (mAs) : should be as low as consistent with required image quality
3.9 Reconstruction algorithm : soft tissue
3.10 Window width : 150 - 400 HU
3.11 Window level : 30 - 50 HU (enhanced examination)
0 - 30 HU (unenhanced examination)
4. CLINICAL CONDITIONS WITH IMPACT ON GOOD IMAGING PERFORMANCE
4.1 Motion - movement artefact deteriorates the image quality. This is prevented by a standard breath-hold technique; alternatively if this is not possible scan during quiet respiration
4.2 Intravenous contrast media - useful for delineation of tumorous or inflammatory disease
  - scanning early after injection of intravenous contrast media is useful for detection of intrapancreatic tumours
4.3 Problems and pitfalls - inconsistent breath holding between slices may obscure subtle pathology in serial CT
  - insufficient differentiation of pancreatic head and duodenum due to lack of oral contrast media in duodenum
  - insufficient pancreatic delineation in patients with reduced retroperitoneal fatty tissue
4.4 Modification to technique - bowel motion may require spasmolytic therapy
  - the examination may be extended to include the liver with contrast in the portovenous phase in the case of tumour suspicion
  - intra-arterial contrast media may be used for detection of endocrine pancreatic tumours